uvrA
b4058
ECK4050 |
ATPase and DNA damage
recognition protein of
nucleotide excision
repair excinuclease
UvrABC
|
| |
| Gene Synonyms |
| uvrA;dinE;dar; |
| Gene Product |
| Length |
Gene Type |
E.C Number(s) |
| 940 |
Enzyme |
None |
| Structural Domain Assignments (
Superfamily ) |
| Module (click for details) |
Superfamily ID |
Domain Annotation |
|
b4058 |
52540 |
P-loop containing nucleoside triphosphate hydrolases |
|
b4058 |
52540 |
P-loop containing nucleoside triphosphate hydrolases |
| Method of Assignment |
| Experimental |
| Literature Reference(s) |
| Sl.No |
Author(s) |
Journal |
Title |
Volume |
Year |
Pages |
REFID |
| 1 |
Zou, Y. and Van Houten, B. |
EMBO J. |
Strand opening by the UvrA(2)B complex allows dynamic recognition of DNA damage |
18 |
1999 |
4889 - 4901 |
10469667
|
| 2 |
Claassen, L. A. and Grossman, L. |
J.Biol.Chem. |
Deletion mutagenesis of the Escherichia coli UvrA protein localizes domains for DNA binding, damage recognition, and protein-protein interactions |
266 |
1991 |
11388 - 11394 |
1828248
|
| 3 |
Goosen, N. and Moolenaar, G. F. |
Research.in Microbiology |
Role of ATP hydrolysis by UvrA and UvrB during nucleotide excision repair |
152 |
2001 |
401 - 409 |
11421287
|
| 4 |
Verhoeven, E. E., Wyman, C., Moolenaar, G. F., and Goosen, N. |
EMBO J. |
The presence of two UvrB subunits in the UvrAB complex ensures damage detection in both DNA strands |
21 |
2002 |
4196 - 4205 |
12145219
|
| 5 |
Caron, P. R. and Grossman, L. |
Nucleic Acids Res. |
Incision of damaged versus nondamaged DNA by the Escherichia coli UvrABC proteins |
16 |
2008 |
7855 - 7865 |
2843804
|
| 6 |
Koo, H. S., Claassen, L., Grossman, L., and Liu, L. F. |
Proc.Natl.Acad.Sci.U.S.A. |
ATP-dependent partitioning of the DNA template into supercoiled domains by Escherichia coli UvrAB |
88 |
1991 |
1212 - 1216 |
1847511
|
| 7 |
Mazur, S. J. and Grossman, L. |
Biochemistry |
Dimerization of Escherichia coli UvrA and its binding to undamaged and ultraviolet light damaged DNA |
30 |
1991 |
4432 - 4443 |
1827034
|
| Physiological Role(s) |
Information transfer --> DNA related --> DNA repair
Cell processes --> Protection --> Radiation
Cell processes --> SOS response
| Location of gene products --> Cytoplasm |
| Links to related Databases |
| GenBank (GI) |
SwissProt |
EcoGene |
EchoBASE |
|
2367343 |
P07671 |
EG11061 |
EB1054 |
| |
| Sequence Similar Group(s) Click to see members |
| No Group Assignment
|
|
| |