GenProtEC Query: b2684

mprA
b2684
ECK2678
DNA-binding transcriptional regulator
Gene Synonyms
mprA;emrR;emrA;
Gene Product
Length Gene Type E.C Number(s)
176 Regulatory protein None
Structural Domain Assignments ( Superfamily )
Module (click for details) Superfamily ID Domain Annotation
b2684 46785 Winged helix DNA-binding domain
Method of Assignment
Experimental
Literature Reference(s)
Sl.No Author(s) Journal Title Volume Year Pages REFID
1 Brooun, A., Tomashek, J. J., and Lewis, K. J.Bacteriol. Purification and ligand binding of EmrR, a regulator of a multidrug transporter 181 1999 5131 - 5133 10438794
2 del Castillo, I., Gomez, J. M., and Moreno, F. J.Bacteriol. mprA, an Escherichia coli gene that reduces growth-phase- dependent synthesis of microcins B17 and C7 and blocks osmoinduction of proU when cloned on a high-copy-number plasmid 172 1990 437 - 445 2152912
3 del Castillo, I., Gonzalez-Pastor, J. E., San Millan, J. L., and Moreno, F. J.Bacteriol. Nucleotide sequence of the Escherichia coli regulatory gene mprA and construction and characterization of mprA-deficient mutants 173 1991 3924 - 3929 1840583
4 Mao, W. and Siegele, D. A. Mol.Microbiol. Genetic analysis of the stationary phase-induced mcb operon promoter in Escherichia coli 27 1998 415 - 424 9484896
Physiological Role(s)
Information transfer --> RNA related --> Transcription related
Regulation --> Type of regulation --> Transcriptional level --> Repressor
Regulation --> Genetic unit regulated --> Operon (regulation of one operon)
Cell processes --> Protection --> Drug resistance/sensitivity
Location of gene products --> Cytoplasm
extrachromosomal --> Plasmid related
Links to related Databases
GenBank (GI) SwissProt EcoGene EchoBASE
1789040 P24201 EG10603 EB0598
Sequence Similar Group(s) Click to see members
transcriptional repressor of multidrug resistance pump (MarR family)


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