GenProtEC Query: b2159

nfo
b2159
ECK2152
endonuclease IV with intrinsic 3'-5' exonuclease activity
Gene Synonyms
nfo
Gene Product
Length Gene Type E.C Number(s)
285 Enzyme 3.1.21.2
Structural Domain Assignments ( Superfamily )
Module (click for details) Superfamily ID Domain Annotation
b2159 51658 Xylose isomerase-like
Method of Assignment
Experimental
Literature Reference(s)
Sl.No Author(s) Journal Title Volume Year Pages REFID
1 Serafini, D. M. and Schellhorn, H. E. Can.J.Microbiol. Endonuclease III and endonuclease IV protect Escherichia coli from the lethal and mutagenic effects of near-UV irradiation 45 1999 632 - 637 10497792
2 Kerins, S. M., Collins, R., and McCarthy, T. V. J.Biol.Chem. Characterization of an endonuclease IV 3'-5' exonuclease activity 5 2003 3048 - 3054 12444080
3 Souza, L. L., Eduardo, I. R., Padula, M., and Leitao, A. C. Mutagenesis Endonuclease IV and exonuclease III are involved in the repair and mutagenesis of DNA lesions induced by UVB in Escherichia coli 21 2006 125 - 130 16524897
4 Haring, M., Rudiger, H., Demple, B., Boiteux, S., and Epe, B. Nucleic Acids Res. Recognition of oxidized abasic sites by repair endonucleases 22 1994 2010 - 2015 7518077
5 Takeuchi, M., Lillis, R., Demple, B., and Takeshita, M. J.Biol.Chem. Interactions of Escherichia coli endonuclease IV and exonuclease III with abasic sites in DNA 269 1994 21907 - 21914 7520446
6 Levin, J. D., Johnson, A. W., and Demple, B. J.Biol.Chem. Homogeneous Escherichia coli endonuclease IV. Characterization of an enzyme that recognizes oxidative damage in DNA 263 1988 8066 - 8071 2453510
Physiological Role(s)
Metabolism --> Macromolecule degradation --> DNA
Information transfer --> DNA related --> DNA degradation
Cell processes --> Protection --> Radiation
Links to related Databases
GenBank (GI) SwissProt EcoGene EchoBASE
1788483 P12638 EG10651 EB0645
Sequence Similar Group(s) Click to see members
No Group Assignment


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