ogt
b1335
ECK1331 |
O-6-alkylguanine-DNA:cyst
eine-protein
methyltransferase
|
| |
| Gene Synonyms |
| ogt |
| Gene Product |
| Length |
Gene Type |
E.C Number(s) |
| 171 |
Enzyme |
2.1.1.63 |
| Structural Domain Assignments (
Superfamily ) |
| Module (click for details) |
Superfamily ID |
Domain Annotation |
|
b1335 |
46767 |
Methylated DNA-protein cysteine methyltransferase, C-terminal domain |
| Method of Assignment |
| Experimental |
| Literature Reference(s) |
| Sl.No |
Author(s) |
Journal |
Title |
Volume |
Year |
Pages |
REFID |
| 1 |
Rebeck, G. W. and Samson, L. |
J.Bacteriol. |
Increased spontaneous mutation and alkylation sensitivity of Escherichia coli strains lacking the ogt O6-methylguanine DNA repair methyltransferase |
173 |
1991 |
2068 - 2076 |
2002008
|
| 2 |
Potter, P. M., Wilkinson, M. C., Fitton, J., Carr, F. J., Brennand, J., Cooper, D. P., and Margison, G. P. |
Nucleic Acids Res. |
Characterisation and nucleotide sequence of ogt, the O6- alkylguanine-DNA-alkyltransferase gene of E. coli |
15 |
1987 |
9177 - 9193 |
2825131
|
| 3 |
Mackay, W. J., Han, S., and Samson, L. D. |
J.Bacteriol. |
DNA alkylation repair limits spontaneous base substitution mutations in Escherichia coli |
176 |
1994 |
3224 - 3230 |
8195077
|
| 4 |
Ferrezuelo, F., Prieto-Alamo, M. J., Jurado, J., and Pueyo, C. |
Environ.Mol.Mutagen. |
Influence of DNA repair by (A)BC excinuclease and Ogt alkyltransferase on the distribution of mutations induced by n- propyl-N-nitrosourea in Escherichia coli |
31 |
1998 |
82 - 91 |
9464319
|
| Physiological Role(s) |
Information transfer --> DNA related --> DNA restriction/modification
Regulation --> Type of regulation --> DNA structure level --> Methylation
| Location of gene products --> Cytoplasm |
| Links to related Databases |
| GenBank (GI) |
SwissProt |
EcoGene |
EchoBASE |
|
1787596 |
P09168 |
EG10668 |
EB0662 |
| |
| Sequence Similar Group(s) Click to see members |
| O-6-alkylguanine-DNA/cysteine-protein methyltransferase
|
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