GenProtEC Query: b0676

nagC b0676 ECK0664		DNA-binding transcriptional dual regulator
Gene Synonyms
nagR;nagC;
Gene Product
Length		Gene Type		E.C Number(s)
406		Regulatory protein		None
Structural Domain Assignments ( Superfamily )
Module (click for details)		Superfamily ID	Domain Annotation
b0676		46785	Winged helix DNA-binding domain
b0676		53067	Actin-like ATPase domain
Method of Assignment
Experimental
Literature Reference(s)
Sl.No	Author(s)	Journal	Title	Volume	Year	Pages	REFID
1	Plumbridge, J. and Pellegrini, O.	Mol.Microbiol.	Expression of the chitobiose operon of Escherichia coli is regulated by three transcription factors: NagC, ChbR and CAP	52	2004	437 - 449	15066032
2	Vogler, A. P. and Lengeler, J. W.	Mol.Gen.Genet.	Analysis of the nag regulon from Escherichia coli K12 and Klebsiella pneumoniae and of its regulation	219	1989	97 - 105	2693951
3	Plumbridge, J. A.	J.Gen.Microbiol.	A dominant mutation in the gene for the Nag repressor of Escherichia coli that renders the nag regulon uninducible	138	1992	1011 - 1017	1645125
4	Plumbridge, J. A.	Mol.Microbiol.	Repression and induction of the nag regulon of Escherichia coli K-12: the roles of nagC and nagA in maintenance of the uninduced state	5	1991	2053 - 2062	1766379
5	Plumbridge, J. and Kolb, A.	J.Mol.Biol.	CAP and Nag repressor binding to the regulatory regions of the nagE-B and manX genes of Escherichia coli	217	1991	661 - 679	1848637
Physiological Role(s)
Metabolism --> Central intermediary metabolism --> Amino sugar conversions
Information transfer --> RNA related --> Transcription related
Regulation --> Type of regulation --> Transcriptional level --> Activator
Regulation --> Type of regulation --> Transcriptional level --> Repressor
Regulation --> Type of regulation --> Posttranscriptional --> Translation attenuation and efficiency
Regulation --> Genetic unit regulated --> Operon (regulation of one operon)
Location of gene products --> Cytoplasm
Links to related Databases
GenBank (GI)		SwissProt		EcoGene		EchoBASE
1786891		P15301		EG10636		EB0630
Sequence Similar Group(s) Click to see members
transcriptional repressor of genes for catabolic enzymes (NagC/XylR (ROK) family)

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