GenProtEC Query: b0642

leuS
b0642
ECK0635
leucyl-tRNA synthetase
Gene Synonyms
syl;leuS;
Gene Product
Length Gene Type E.C Number(s)
860 Enzyme 6.1.1.4
Structural Domain Assignments ( Superfamily )
Module (click for details) Superfamily ID Domain Annotation
b0642 50677 ValRS/IleRS/LeuRS editing domain
b0642 52374 Nucleotidylyl transferase
b0642 47323 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Method of Assignment
Experimental
Literature Reference(s)
Sl.No Author(s) Journal Title Volume Year Pages REFID
1 Williamson, R. M. and Oxender, D. L. Proc.Natl.Acad.Sci.U.S.A. Sequence and structural similarities between the leucine- specific binding protein and leucyl-tRNA synthetase of Escherichia coli 87 1990 4561 - 4565 2191293
2 Whittaker, J. J. and Jackson, J. H. Biochem.Biophys.Res.Commun. Maintenance of repression control of the ilvGMEDA operon in a temperature-sensitive leucyl-transfer RNA synthetase mutant of Escherichia coli K-12 at a restrictive temperature 187 1992 1106 - 1112 1530607
3 Hsu, J. L., Rho, S. B., Vanella, K. M., and Martinis, S. A. J.Biol.Chem. Functional divergence of a unique C-terminal domain of leucyl-tRNA synthetase to accommodate its splicing and aminoacylation roles 281 2006 23075 - 23082 16774921
Physiological Role(s)
Information transfer --> Protein related --> Amino acid-activation
Location of gene products --> Cytoplasm
Links to related Databases
GenBank (GI) SwissProt EcoGene EchoBASE
1786861 P07813 EG10532 EB0527
Sequence Similar Group(s) Click to see members
leucine tRNA synthetase


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