leuS b0642 ECK0635 |
leucyl-tRNA synthetase
|
| |
| Gene Synonyms |
| syl;leuS; |
| Gene Product |
| Length |
Gene Type |
E.C Number(s) |
| 860 |
Enzyme |
6.1.1.4 |
| Structural Domain Assignments (
Superfamily ) |
| Module (click for details) |
Superfamily ID |
Domain Annotation |
|
b0642 |
50677 |
ValRS/IleRS/LeuRS editing domain |
|
b0642 |
52374 |
Nucleotidylyl transferase |
|
b0642 |
47323 |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| Method of Assignment |
| Experimental |
| Literature Reference(s) |
| Sl.No |
Author(s) |
Journal |
Title |
Volume |
Year |
Pages |
REFID |
| 1 |
Williamson, R. M. and Oxender, D. L. |
Proc.Natl.Acad.Sci.U.S.A. |
Sequence and structural similarities between the leucine- specific binding protein and leucyl-tRNA synthetase of Escherichia coli |
87 |
1990 |
4561 - 4565 |
2191293
|
| 2 |
Whittaker, J. J. and Jackson, J. H. |
Biochem.Biophys.Res.Commun. |
Maintenance of repression control of the ilvGMEDA operon in a temperature-sensitive leucyl-transfer RNA synthetase mutant of Escherichia coli K-12 at a restrictive temperature |
187 |
1992 |
1106 - 1112 |
1530607
|
| 3 |
Hsu, J. L., Rho, S. B., Vanella, K. M., and Martinis, S. A. |
J.Biol.Chem. |
Functional divergence of a unique C-terminal domain of leucyl-tRNA synthetase to accommodate its splicing and aminoacylation roles |
281 |
2006 |
23075 - 23082 |
16774921
|
| Physiological Role(s) |
Information transfer --> Protein related --> Amino acid-activation
| Location of gene products --> Cytoplasm |
| Links to related Databases |
| GenBank (GI) |
SwissProt |
EcoGene |
EchoBASE |
|
1786861 |
P07813 |
EG10532 |
EB0527 |
| |
| Sequence Similar Group(s) Click to see members |
| leucine tRNA synthetase
|
|