GenProtEC Query: b0115

aceF
b0115
ECK0114
pyruvate dehydrogenase, dihydrolipoyltransacetyla se component E2
Gene Synonyms
aceF
Gene Product
Length Gene Type E.C Number(s)
630 Enzyme 2.3.1.12
Structural Domain Assignments ( Superfamily )
Module (click for details) Superfamily ID Domain Annotation
b0115 51230 Single hybrid motif
b0115 51230 Single hybrid motif
b0115 51230 Single hybrid motif
b0115 47005 Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
b0115 52777 CoA-dependent acyltransferases
Method of Assignment
Experimental
Literature Reference(s)
Sl.No Author(s) Journal Title Volume Year Pages REFID
1 Schulze, E., Westphal, A. H., Veenhuis, M., and de Kok, A. Biochim.Biophys.Acta Purification and cellular localization of wild type and mutated dihydrolipoyltransacetylases from Azotobacter vinelandii and Escherichia coli expressed in E. coli 1120 1992 87 - 96 1554745
2 Schulze, E., Westphal, A. H., Obmolova, G., Mattevi, A., Hol, W. G., and de Kok, A. Eur.J.Biochem. The catalytic domain of the dihydrolipoyl transacetylase component of the pyruvate dehydrogenase complex from Azotobacter vinelandii and Escherichia coli. Expression, purification, properties and preliminary X-ray analysis 201 1991 561 - 568 1935951
3 Danson, M. J., Hale, G., Johnson, P., Perham, R. N., Smith, J., and Spragg, P. J.Mol.Biol. Molecular weight and symmetry of the pyruvate dehydrogenase multienzyme complex of Escherichia coli 129 1979 603 - 617 383998
Physiological Role(s)
Metabolism --> Carbon compound utilization --> Carbohydrates/Carbon compounds --> Glycol degradation
Metabolism --> Energy metabolism (carbon) --> Pyruvate dehydrogenase
Metabolism --> Energy metabolism (carbon) --> Anaerobic respiration
Metabolism --> Central intermediary metabolism --> Glyoxylate degradation
Metabolism --> Central intermediary metabolism --> Lactate oxidation
Links to related Databases
GenBank (GI) SwissProt EcoGene EchoBASE
1786305 P06959 EG10025 EB0024
Sequence Similar Group(s) Click to see members
pyruvate dehydrogenase, dihydrolipoyltransacetylase subunit


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