Paralogous Groups of E. coli Proteins Ordered by Size

Sequence similarity is limited to PAM 200 for alignments of at least 83 amino acids.
The protein groups are clustered by transitive relationships.

Number of Members [Click to view members]		Group Function
93		transport protein (ABC superfamily transporter, atp_bind)
52		transport protein (ABC superfamily, membrane)
46		response regulator in two-component regulatory system (LuxR/UhpA and OmpR families)
45		transcriptional regulator (LysR family)
44		transport protein (MFS family)
32		membrane protein
29		transcriptional regulator (GntR family)
24		transrcriptional repressor (GalR/LacI family) / transport protein (ABC superfamily, periplasmic bin
23		transport protein (APC/Dcu family)
22		sensory histidine kinase in two-component regulatory system
21		putative fimbrial-like adhesin protein
20		oxidoreductase
18		dehydrogenase, NAD(P)-binding
18		oxidoreductase, NAD(P)-binding
16		transcriptional regulator (AraC/XylS family)
15		transposase/IS protein
14		sigma54 activator protein, enhancer binding protein (EBP family)
13		aldehyde dehydrogenase
13		oxidoreductase
12		transport protein (ABC superfamily, membrane)
11		sugar kinase
11		PTS family enzyme IIA
11		recombinase
11		IS5 protein
11		periplasmic chaperone protein
10		outer membrane protein
10		oxidoreductase
9		transport protein (NCS2 family)
9		phosphatase
9		transport protein (ABC superfamily, peri_bind)
9		acyltransferase
9		oxidoreductase, NAD(P)-dependent
8		GTP-binding protein/elongation factor
8		transport protein (ABC superfamily, peri_bind)
8		ligase, CoA-dependent, ATP-binding
8		transcriptional repressor (IclR family)
8		IS2 protein
8		outer membrane porin
8		Nudix hydrolase
8		membrane protein
7		aminotransferase, PLP-dependent
7		RNA helicase, ATP-dependent
7		conserved protein
7		dehydratase, NAD(P) binding
7		S-transferase
7		membrane protein
7		transport protein (DASS, DcuC, DASS, GntP family)
7		alcohol dehydrogenase
7		transport protein (RND family)
7		acyltransferase
7		crotonase (enoyl CoA hydratase)
7		transport protein (ABC superfamily, membrane)
7		aminotransferase, PLP-dependent
7		conserved protein
7		outer membrane protein
7		kinase/transcriptional regulator (NagC/XylR (ROK) family)
6		decarboxylase, TPP dependent
6		sugar kinase
6		tRNA/rRNA methyltransferase
6		dehydratase, PLP-dependent
6		putative tail fiber assembly protein
6		conserved protein with phosphatase-like domain
6		conserved hypothetical protein
6		transport protein (GPH family)
6		IS1 protein, InsA
6		IS1 protein, InsB
5		conserved protein
5		tRNA synthetase
5		transport protein (HAAP/MFS family)
5		oxidoreductase
5		membrane protein
5		dehydrogenase/reductase
5		transferase
5		dehydrogenase, NAD(P)-binding
5		thiolase
5		methyl-accepting chemotaxis protein
5		oxidoreductase
5		PTS family enzyme I
5		PTS family enzyme IIB
5		transport protein (HAAAP family)
5		transport protein / membrane protein
5		putative regulator
5		epimerase/aldolase
5		ligase
5		putative transposase
5		decarboxylase
5		outer membrane porin
5		transposase-related protein
5		transport protein (RhtB family)
5		acyltransferase
5		PTS family enzyme IIC
5		conserved protein
5		membrane protein
5		flavoprotein with adenine nucleotide-binding domain
5		transcriptional regulator (MerR family)
5		conserved protein/membrane protein
4		putative pyruvate formate lyase
4		conserved hypothetical protein
4		membrane protein / transport protein (ABC superfamily, membrane)
4		putative transport protein (POT family)
4
4		PTS family enzyme IIC
4		carboxypeptidase
4		pyruvate formate lyase activating enzyme
4		pseudouridine synthase
4		oxidoreductase
4		transport protein (DAACS family)
4		sugar aldolase
4		putative membrane protein
4		oxidoreductase
4		ATP synthase
4		transport protein (MFS family)
4		PTS family enzyme IIBC
4		synthase
4		transport protein (SMR superfamily)
4		chaperone/ATPase
4		putative oxidoreductase/flavoprotein
4		pseudoruidine/pseudouridylate synthase
4		transglycosylase
4
4		unknown
4		aminopeptidase
4		lipoprotein
4		prophage protein
4		DNA repair protein
4		dehydrogenase/reductase
4		rhs protein
4		transport protein (P-type ATPase family)
4		membrane protein
4		DNA-binding protein
4		dehydratase
4		synthase
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